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Paroxetine
Hello Doctor,
I have been taking Paroxetine CR 12.5 mg for the last 1 month for premature ejaculation, general anxiety, and mild depression. Earlier I was using Proxy CR 12.5 by Wilwin Laboratories, which was working well for me.
Since that brand was not available, I switched to Paxidep CR 12.5 by Sun Pharmaceutical Industries about 4–5 days ago. After switching, I feel it is slightly less effective and I am experiencing more anxiety than before.
I am also having daytime drowsiness that interferes with my daily routine, and regular stomach disturbance with loose stools.
Is it okay to switch between these brands since both contain Paroxetine CR 12.5 mg? Do different brands sometimes feel less effective? Should I continue this brand for some time or try to find the previous one?
Thank you.
Answers (4)
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It’s very common for mental distress to manifest as physical symptoms—what we call the mind-body connection. Your nervous system is likely in a state of 'high alert,' which affects everything from your sleep to your digestion.
As a psychiatrist, I look at the whole picture—your physical health, your environment, and your neurochemistry. Understanding these links is the first step toward relief. I invite you to a consultation where we can break down these symptoms scientifically and build a management plan that works for your specific lifestyle.
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Hi..yes. both are same medicines. Sometimes CR and IR preparations have different efficacy if taken at different timings ... Usually taking the medicine 3 to 4 hours before sexual activity is advisable. Wait for few days and see
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Dr. Md Arshad Ayub
Addiction Psychiatrist
6 yrs exp
Gaya
Yes, both brands contain Paroxetine CR 12.5 mg, so in principle they should have similar effects.
Since you have switched only 4–5 days ago, it may be too early to judge effectiveness. Paroxetine usually takes 2–3 weeks to stabilize after any change. The increased anxiety, drowsiness, and loose stools can be temporary adjustment side effects and often settle within 1–2 weeks.
If symptoms are tolerable, you can continue the current brand for another 1–2 weeks and monitor. If the side effects persist or effectiveness remains lower, you may try to switch back to the previous brand if available, or consult your doctor for dose adjustment or alternative options.
Also, taking the medication at night may help reduce daytime drowsiness.
If symptoms worsen significantly, do consult your doctor earlier.
Dr Md. Arshad Ayub
Contact: nine nine three one zero four five zero zero eight
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.