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Male 36Y 137kg 147/100 Sudden weightloss
Hi All,
I have undergone medical test recently and diagnosed with hba1cb at 8.1 and grade 3 fatty liver. Above are my measurements. My ldl cholesterol is 123mg. Doctor advised to take empastat 12.5+500 mg, obimet sr 500 mg, rosuvas 10mg, telista 40mg on daily basis for mrng and night. My weight at the time of report was 137 and after taking medicines and within a week i am now at 131 kg.. i don't feel hungry nowadays and is this weight loss normal since my initial weight is very high. Or i need to check with doctor again for this sudden weight loss.
Answers (17)
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Within a week 5 kg weight loss is abnormal .follow up
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It is common with the medication
Take proper hydration
Consult for further treatment aspects
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Your weight loss is due to the meds, but continue them, as you have high hba1c, indicating high blood glucose levels within past 3 months.
Just maintain a healthy diet with no sugar, low fats.
Repeat hba1c and lipid profile after 12 weeks.
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Greetings
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HbA1c 8.1 suggests uncontrolled diabetes and grade 3 fatty liver is commonly associated with obesity and insulin resistance. Mild early weight loss after starting diabetic medicines like empagliflozin/metformin can occur due to reduced appetite, fluid loss, and better sugar control.
Next Steps
-Continue prescribed medicines regularly
-Monitor:
-Fasting/PP sugars weekly
-HbA1c every 3 months
-LFT, RFT, urine routine periodically
-if there is Weight loss >8–10 kg/month, vomiting, severe weakness, or dehydration → review doctor earlier.
-Low-carb diet, avoid sugary drinks/alcohol, regular walking daily,reduce weight gradually
-Stay hydrated as empagliflozin can increase urination
-Contact me anytime on Practo for further consultation
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Continue the same
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Can help you, kindly consult and provide detailed history for proper diagnosis and further management
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Some initial weight loss and reduced appetite can happen after starting diabetes weight related medicines, especially with high starting weight and uncontrolled sugars, so this is not alarming. But your HbA1c and fatty liver do need proper monitoring and a long term plan. Please consult with me once I’ll guide you regarding whether this weight loss pattern is appropriate, medication effects and the safest way to continue treatment.
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With medicine weight loss is normal. Loss of appetite??
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"While a 6 kg weight loss in one week seems dramatic, in your specific clinical scenario, it is largely expected and often beneficial. The medication Empastat (Empagliflozin) works by removing excess glucose through your urine, which also causes a significant 'diuretic effect' (loss of water weight). Additionally, at an initial weight of 137 kg, the body rapidly sheds inflammation and fluid when starting intensive treatment for diabetes. The loss of appetite is a very common side effect of Metformin (Obimet) as your body adjusts to the medication. However, because the drop is rapid, we must ensure it stays within a safe physiological range."
Next Steps
Managing Metformin: "The appetite loss and stomach discomfort usually subside within 2 weeks. Try taking your Metformin doses during or immediately after a meal to minimize these side effects."
Liver Health: "Your Grade 3 Fatty Liver is a major metabolic risk. This weight loss, as long as it stabilizes to 1–2 kg per week after the initial drop, is the single most effective way to reverse liver fat and lower your HbA1c."
Caution: "Do not stop your medications due to the weight loss without a doctor's guidance. Sudden stopping of Telmisartan can cause a dangerous 'rebound' spike in blood pressure."
Red Flags: "Seek immediate medical attention if you experience extreme nausea, persistent vomiting, severe abdominal pain, or a 'fruity' breath odor, as these can be signs of a rare but serious condition called Euglycemic Ketoacidosis associated with your new medication."
Health Tips
To review your electrolyte levels and adjust your Metformin dosage if the appetite loss prevents you from eating entirely, please book a full consultation session via my Practo profile."
You are in a critical 'reset' phase for your metabolism; while the first week was fast, we will aim for a steadier pace moving forward to safely reverse your fatty liver. Please book a full session with me for better treatment plan and advice on practo app...
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Dr. Vetsa Sri Krishna Chaitanya
General Physician
7 yrs exp
Rajahmundry
Need a few more details please consult for further evaluation and treatment
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Dr. Ashita Kuruvilla
General Practitioner
8 yrs exp
Kolkata
Need few more details for further evaluation. Kindly consult
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Dr. Gaurav Jaiswal
General Physician
7 yrs exp
Jhansi
Kindly do connect and consult
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Dr. Chaithra H
General Physician
5 yrs exp
Bangalore
Pls check with doctor
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Dr. Suraj Sharma
General Practitioner
4 yrs exp
Jaipur
Do consult
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Dr. Ravi Kumar Nadella
General Physician
18 yrs exp
Hyderabad
It happens with medw
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