Hello Doctor,
My baby boy is 2 months old and diagnosed with focal onset seizures. EEG showed left parietal-temporal epileptiform discharges. MRI brain and neurosonogram were normal.
He was started on Levepsy (Levetiracetam) 100 mg/ml syrup. After starting treatment, seizures reduced significantly for about 15 days. Recently, I noticed mild abnormal movements again (less severe than earlier). The doctor has increased the dose.
Is it common to have breakthrough seizures while on medication? Will seizures reduce completely after dose adjustment? Does this condition improve with age in infants? Do we need further tests like genetic or metabolic evaluation?
Baby is feeding well and otherwise active. Kindly advise regarding prognosis and further management.
Answers (3)
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As per the history, we cant rule out various types of epilepsies in this age group
In 2M old boy causes might be
1) Familial epilepsy - usually subsides as child grows (require treatment and tappering the dose as per symptoms)
2) Genetic Epilepsy- might require Epilepsy gene panel
3) Organic cause like cortical dysplasia - bit usually seen on MRI
4) Metabolic diseases and electrolyte imbalance - Needs metabolic dis panel
5) post infectious - unlikely in ur case as no history of fever/ infection
And yes, break through seizures are common in children due to rapid metabolism of anti epileptic drugs as child growth is more compared to adult
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.
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