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Seeking Advice on Liver Monitoring While
I’m on Agomelatine, which my doctor says could be liver toxic. I need to get a liver function test (LFT) every 20 days, but it’s quite expensive.
If Agomelatine affects the liver, which specific markers (e.g., SGOT, SGPT, Total Bilirubin) should I monitor? Is it necessary to do the full LFT every time, or can I focus on just a few tests?
Thanks for any guidance!
Answers (4)
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Dr. Nidhi Marvania Raja
Psychiatrist
8 yrs exp
Mumbai
Agomelatine can have impact on your liver but not always so. It’s relatively safe for daily use. Doctor may have cautioned you about its side effects but that doesn’t mean you have to take the test every 20 days.
You can take it every 3-6 months if you want to be cautious. That too SGOT and SGPT suffices and don’t need to go for all the parameters.
Rise in bilirubin over the normal range usually reflects in your body in form of jaundice - yellowing of sclera, skin, nausea, vomiting etc. is any such symptom develop you should be cautious, rest nothing to worry about.
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Avoid smoking and alcohol.
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Dr. Shailaja Bandla
Addiction Psychiatrist
20 yrs exp
Vijayawada
Hi.. there are other sleep medicines which are not toxic to the liver. However will need further history regarding your condition to advise appropriately. Usually serum transaminases increase more than three times the upper limit of normal if there is toxicity due to agomelatin.
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consult online for further evaluation and management
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Dr. Bhavya S. Bhalodia
Psychiatrist
3 yrs exp
Rajkot
For preliminary screening SGPT can be done. If required full LFT should be done. Kindly discuss your concern with treating Doctor.
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For preliminary screening SGPT can be done. If required full LFT should be done. Kindly discuss your concern with treating Doctor.
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.