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Irritation spikes
I am on venlafaxine 225mg and olenzapine 2.5mg..my mood is ok but I still get irritated spikes sometimes and those spikes are like what someone said or did to me not of future... sometimes too irritable i fight with person in my mind..
Answers (3)
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It is a positive sign that your overall mood is stable on venlafaxine 225 mg and olanzapine 2.5 mg. However, the sudden spikes of irritation, mental arguments, and getting triggered by things people said or did in the past suggest residual emotional reactivity rather than a relapse of depression.
These symptoms are commonly seen when there is underlying anxiety, rumination, poor frustration tolerance, or unresolved anger, even when mood is otherwise okay. Sometimes, antidepressants can improve mood but not fully control irritability or intrusive mental replay, which is what you seem to be describing.
This does not mean treatment has failed—it means the treatment may need fine-tuning.
Next Steps
• Discuss these symptoms openly with your treating psychiatrist
• Your doctor may consider:
Adjusting the dose or timing of current medicines
Optimising olanzapine or considering an alternative mood-stabilising option
Addressing anxiety/rumination specifically
• Psychotherapy (CBT or emotion-regulation focused therapy) is very helpful for mental arguments, triggers, and irritability
• Practice pause techniques when irritated (delay response, grounding, slow breathing)
Health Tips
For more queries, Reach out for an online or in-person consultation:
📞 NEURONAL FIX CLINIC, RAMPRASTHA COLONY, Ghaziabad, (near Shreshtha Vihar, Delhi)- +91- 74XX52XX97XX67XX61
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Hello Sir
Venlafaxine is in good dosage
It controls good amount of anger
Sometimes there occurs episodes of irritation and response to it
That can be controlled with some medicines if required and also counselling/ therapy for further better management of anger issues and also to reduce your medicines and stop in due course
Next Steps
kindly contact me on seven nine seven four six zero eight one nine nine or kindly consult online for further management and treatment
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Try discussing with your psychiatrist if adding a mood stabiliser would help
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.