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Cbc report
My husband is 35 years old and has fluctuating platelet counts on recent CBC tests:
- 5–6 months ago: 176k
- 3 months ago: 122k
- Recent Redcliffe: 92k
- Orange Health (CBC + smear): 150k, smear normal
- Apollo: 111k, comment: Giant platelets noted, MPV high
(13.5)
WBC has been normal in all reports, hemoglobin around normal, no bruising/bleeding, no fever, no weight loss.
He has chronic gut symptoms: bloating, acidity, loose motions sometimes, urgency/frequency of stools.
Please advise:
1. Are these fluctuating platelet counts concerning?
2. Can giant platelets/high MPV cause falsely low platelet count?
3. What could be the likely cause?
4. Which specialist should we see first: hematologist or gastroenterologist?
5. What further tests should be done?
Please guide.
Answers (11)
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Please share detailed medical history, why tests were done? Because it is symptoms and disease which is treated, but not results.
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Mild fluctuations like this with normal smear and no symptoms are usually not serious 👍
Giant platelets can sometimes affect automated counts, so variation can happen.
I can help you with a clear evaluation plan what tests are actually needed book a quick consult 👍
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The combination of fluctuating platelet counts, 'giant platelets' on smear, and chronic gastrointestinal symptoms (bloating, loose motions) requires a unified clinical look. While a platelet count of 92k–150k is generally not an emergency in the absence of bleeding, the presence of Giant Platelets and high MPV (13.5) suggests that the bone marrow is actively responding to a peripheral demand or an inflammatory trigger, potentially located in the gut.
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The high MPV and giant platelets are a significant clue. They often indicate that the marrow is healthy but the gut is not absorbing the 'building blocks' properly. A detailed clinical consultation is necessary to bridge these hematological findings with the GI symptoms. Please share the full reports so I can help determine if this is a case of malabsorption-linked thrombocytopenia."
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Yes,its concerning
Yes.
Its due to various reasons like any ongoing infection,defective bone marrow thrombocytosis,factor deficiency etc.
Both concerns required, hematologist first ,then gastroenterologist.
H.pylori,ph manometry.ugie,b12,crp.
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Consult superspecialist like haematology
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Dr. Vetsa Sri Krishna Chaitanya
General Physician
7 yrs exp
Rajahmundry
Need a few more details please consult for further evaluation and treatment
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Dr. Anuj Mothsra
General Physician
6 yrs exp
Jhunjhunu
Can help you, kindly consult and provide detailed history for proper diagnosis and further management
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Dr. Ravi Kumar Nadella
General Physician
18 yrs exp
Hyderabad
Its concerning
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Dr. Suraj Sharma
General Practitioner
4 yrs exp
Jaipur
Do consult
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Dr. Chaithra H
General Physician
5 yrs exp
Bangalore
Get immature platelet fraction done
Get thyroid profile done and have a follow up
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