Sign of depression. Please help me out.

My wife whose age is 32 years is suffering from depression as I think. We got married in 2005 and we have 10 years old son. There were issues between my parents and my wife at the time of marriage. For more than 07 years, she is living away from my parents with me. Still she don't want to forget those things. For one year, she was with me in Kochi, Kerala. After that, she moved with me to Goa for 05 years. And in April 16, she came with me to Mumbai. Now the situation is getting worse day by day. She started become angry without any reason. She is suffering from breathing problems in night but she don't want to go to doctor even after insisting so many times. She is very keen towards cleaning of house. She forgets everything except cleaning of home. My son is also getting irritated with this. His education is also getting affected. Now a days, if she sees even a fold in the bedsheet, she starts shouting and crying saying that her life is ruined. Please help me out.