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Seeking Treatment options for cancer
Seeking expert opinion for a 62F with signet ring cell carcinoma of sigmoid colon diagnosed July 2025. She underwent surgery (LAR + hysterectomy + BSO) followed by chemotherapy (Dacotin + Capecitabine). Latest PET-CT Feb 2026 shows no liver, lung, brain metastasis and no residual primary lesion. However, there are FDG-avid peritoneal nodules (SUV ~7) with mild ascites, suggestive of post-op changes vs residual disease. Kindly advise on further management, chemotherapy strategy, CRS alone or CRS with HIPEC suitability or second line chemo.
Answers (1)
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Dr. Rohit Kashyap
Surgical Oncologist
14 yrs exp
Gorakhpur
FDG avid peritoneal nodules may be due to residual disease. It needs correlation with CEA levels to be certain.
Signet ring cell carcinoma is an aggressive histology .
It needs prompt treatment.
Regarding strategy for further management , it can be judged by seeing the patient along with reports.
Such patients require personalised treatments.
Next Steps
Consult Surgical Oncologists.
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.