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Possible Polycythemia Vera
I am currently being investigated for Polycythemia Vera. I had Hgb of 17.2 and HCT fof 51 back in January. My EPO was at 6.6 and MPN reflex panel was negative for all the known mutations.
I stopped smoking and was on proper hydration for 5 months and re-tested my CBC from two labs
Lab1- Hgb of 15.4 and HCT of 46.2 RBC 5.17
Lab2- Hgb of 16.7 HCT of 49.5 and RBC 5.59
These Lab results are 48 hours apart from each other. Now, I am confused about which one is true?
I do not have any other symptoms, Spleen and Liver normal, no elevation in WBC and PLT.
My haematologist thinks this is normal for age (29 Male).
Kindly help me to understand what are my chances of Triple Negative Polycythemia Vera?
Answers (5)
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Mutations are generally negative in essential thrombocythemia and myelofibrosis.
Blood reports can change with minor variation . Don't worry.Yours are upper limit.
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Don't panic and quit smoking and other drug abuse for good.
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Looks like the values have improved after stopping of smoking and good hydration. These are values just in the upper limit of normal , and is acceptable.
Please select a good lab in your area and limit your testing to that lab alone. Frequent testing will not help. It will just add to your confusion. The variation you see here is day to day variation.
Both these values are acceptable. Not very high.
Check CBC only after 3 months. Shall review then.
Continue ecosprin 75 mg one tab daily
There is no other intervention required as of now.
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Did you relocate from a low altituted region to
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Dr. Tanvi Singh
Medical Oncologist
12 yrs exp
Gwalior
Triple negative PV is extremely rare in adults and is commonly associated with other disorders like Essential thrombocythemia and myelofibrosis
Just keep an check on your CBC report
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Regular checkup is key
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.