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Effect Of Empagliflozin Or Nebivolol ?
My urine ACR level was 5.77 mg/g (Normal <30 mg/gm) on 18/05/2025 i.e just before starting Empagliflozin
Previously it was 2.84 mg/g on 4/4/2025
Serum creatinine,potassium,urea & usg are all within normal limits
Taking Empagliflozin 10 mg once a day for blood sugar & Nebivolol 5 mg once a day for blood pressure since 20 days
Recently noticing foamy & frothy urine
Is it due to empagliflozin or Nebivolol ?
Answers (18)
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Empagliflozolin can cause uti.
It can be bcs of that
Get urine routine test done
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Need few more details
Kindly connect.
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Change Empagliflosin to Metformin 500 If the Hba1c is high
Ace inhibitors are good to decrease proteinuria
Drink lots of fluid
Check Urine Routine Microscopy for Pus cells to rule out UTI
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All ready answered when it is is appeared first time.
Protein is one for frothy urine.
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Foamy or frothy urine can be due to multiple causes.
In this case, since your urine ACR is still within normal range (<30 mg/g) and other parameters like serum creatinine and USG are normal, it's less likely due to kidney damage.
Empagliflozin increases glucose excretion in urine (glucosuria), which may sometimes cause foamy urine — this is usually harmless.
Nebivolol is not known to cause foamy urine or affect urine composition in this way.
However, if foamy urine persists or worsens, repeat urine ACR and consider a urine protein/creatinine ratio to rule out early kidney involvement.
consult
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These drugs generally are considered safe and are not associated with increasing U ACR as side effects.
Although gliflozins are commonly linked to urinary tract infections which may transiently lead to frothy urine with burning sensation.
Be rest assured as U ACR of 5.7 is still way below normal.
Next Steps
If frothing doesn’t stop can go for 24hour urinary protein and urine routine/microscopy
Share reports for further management
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Dr. Sunil Nagar
General Physician
18 yrs exp
Rewa
Connect
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Dr. Shreyas Singh
General Physician
2 yrs exp
Haldwani
Need more details Kindly contact for further consultation with minimum cost
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Dr. Ram Brahma Reddy
General Physician
7 yrs exp
Hyderabad
No
Next Steps
It is because diabetes mellitus
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Dr. Vijay Kumar
Preventive Medicine
7 yrs exp
Tirunelveli
Hi
Foamy frothy urine usually due to protinuria.
You are looking at ACR which is Albumin but other proteins can also released in urine which can cause frothy urine ,for which you have e check PCR.
Neither Empagliflozin or Nebivolol can cause frothy urine
But empagliflozin can cause glycosuria which is release of Glucose in urine.
Empagliflozin can improves the kidney function according to Many trials, you can refer Emperor trial.
That's why your Urea creatinine is improving.
Check Spot PCR ,24 hr Urine PCR for protinuria.
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Dr. Nazia Begum M.G
General Physician
15 yrs exp
Belgaum
Connect will guide you
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Dr. Vinod Kumar Verma
General Physician
9 yrs exp
Gurgaon
-According to your query and sign and symptom you want to know about the cause and Treatment of disease as you have mentioned as above as -
-Please take consultation for better evaluation and best Treatment as it need complete history of patient as personal and family history.
Please follow good life style as
• take plenty of fluid and
• take less spicy and fatty foods and
• take home made food only and
do exercise regularly with yoga and meditation and
• keep positive attitude to fight any disease and any problem of your life .
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Dr. Ravi Kumar Nadella
General Physician
18 yrs exp
Hyderabad
Due to both
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Dr. Manoj Kumar
General Physician
10 yrs exp
Dehradun
Need few more details
Kindly consult
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Dr. Chaithra H
General Physician
5 yrs exp
Bangalore
Needs to be evaluated.
Do consult.
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Dr. Anuj Mothsra
General Physician
6 yrs exp
Jhunjhunu
Can help you, kindly consult and provide detailed history for proper diagnosis and further management
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